Objective To discuss the lipid levels between longevity population and non-longevity population of the Uyghur nationality in Hotan of Xinjiang and its influencing factors.Methods A total of 200 elderly people of natural longevity(90 years old or older) living in Hotan of Xinjiang from 1999 to 2012 were selected as the longevity group,and 123 Uygur non-longevity population(died a natural death from 59 to 73 years old) living in Hotan of Xinjiang and receiving regular follow-up during the same period were taken as non-longevity group.The general information of the two groups was collected,and physical examination and laboratory test of blood lipid indicator were conducted to the two groups.Multivariate Logistic regression analysis was used to explore the influencing factors of longevity population and non-longevity population developing dyslipidemia.Results There was significant difference in gender between the two groups(P<0.05).The smoking rate of the non-longevity group was significantly higher than that of the longevity group(P<0.05).The height and body mass of the non-longevity group were significantly higher than those of the longevity group,while its waist,systolic blood pressure,the incidence of hypertension were significantly lower than those of the longevity group(P<0.05).There was no significant difference in BMI and diastolic blood pressure between the two groups(P>0.05).The total cholesterol(TC),low density lipoprotein cholesterol(LDL-C) and incidence of dyslipidemia in non-longevity group were significantly higher than those in longevity group,while its high density lipoprotein cholesterol(HDL-C) was significantly lower than that of longevity group(P<0.05).There was no significant difference in triacylglycerol(TG) between the two groups(P>0.05).Multivariate Logistic regression analysis showed that gender,waist circumference,systolic blood pressure and hypertension were the influencing factors of longevity population developing dyslipidemia(P<0.05),and gender,BMI was the influencing factors of non-longevity population developing dyslipidemia(P<0.05).Conclusion Longevity and non-longevity populations were both from the Hotan area,but the lipid levels and the incidence of dyslipidemia are significantly different.Gender,waist circumference,systolic blood pressure,high blood pressure is the influencing factors of longevity population developing dyslipidemia,and gender and BMI are the influencing factors of non-longevity population developing dyslipidemia.%目的 探讨新疆和田维吾尔族长寿人群与非长寿人群的血脂水平及影响因素.方法 选取1999-2012年在新疆和田地区生活的维吾尔族自然长寿老年人(年龄≥90岁)200例为长寿组;另选取同期在新疆和田地区生活且接受定期随访的维吾尔族非长寿人群(于59~73岁自然死亡)123例为非长寿组.收集两组一般资料并进行体格检查和实验室血脂指标检测,采用多因素Logistic逐步回归分析探讨长寿人群和非长寿人群患血脂异常的影响因素.结果 两组性别比较,差异有统计学意义(P<0.05);非长寿组吸烟率高于长寿组,差异有统计学意义(P<0.05).非长寿组身高、体质量高于长寿组,腰围、收缩压、高血压发生率低于长寿组,差异有统计学意义(P<0.05);两组BMI、舒张压比较,差异无统计学意义(P>0.05).非长寿组总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、血脂异常发生率高于长寿组,高密度脂蛋白胆固醇(HDL-C)低于长寿组,差异有统计学意义(P<0.05);两组三酰甘油(TG)比较,差异无统计学意义(P>0.05).多因素Logistic逐步回归分析结果显示,性别、腰围、收缩压、高血压是长寿人群发生血脂异常的影响因素(P<0.05),性别、BMI是非长寿人群发生血脂异常的影响因素(P<0.05).结论 长寿人群与非长寿人群均来自和田地区,但血脂水平、血脂异常发生率有明显差异;性别、腰围、收缩压、高血压是长寿人群发生血脂异常的影响因素,性别、BMI是非长寿人群发生血脂异常的影响因素.
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