A型肉毒毒素联合曲安奈德治疗增生性瘢痕效果观察

摘要

目的：探讨A型肉毒毒素联合曲安奈德治疗增生性瘢痕的效果。方法：收治增生性瘢痕患儿74例，分为观察组与对照组各37例。对照组给予曲安奈德注射治疗，观察组给予A型肉毒毒素联合曲安奈德治疗。结果：治疗后1周两组VAS评分均较治疗前降低(P＜0.05)。治疗后3、6个月对照组VAS评分与观察组比较，差异有统计学意义(P＜0.05)。治疗后6个月，观察组总有效率高于对照组(P＜0.05)。结论：A型肉毒毒素联合曲安奈德治疗增生性瘢痕效果优于单纯曲安奈德治疗。%Objective:To investigate the effect of botulinum toxin type A combined with triamcinolone acetonide in the treatment of hypertrophic scar.Methods:74 children with hypertrophic scar were divided into the observation group and the control group, with 37 cases in each group.Patients in the control group were given triamcinolone acetonide injection treatment,while in the observation group were treated with botulinum toxin type A combined with triamcinolone acetonide therapy.Results:After 1 weeks treatment,the VAS scores in the two groups were significantly lower than before the treatment(P<0.05).At the 3th and 6th months after the treatment,there were significant difference in VAS score between the observation group and the control group(P<0.05). After 6 months of treatment,the total effective rate of the observation group was higher than that of the control group(P<0.05). Conclusion:Botulinum toxin type A combined with triamcinolone acetonide in the treatment of hypertrophic scar has better effect than only using triamcinolone acetonide.