再次手术切除与介入栓塞在肝癌术后复发患者中的应用效果

摘要

Objective To investigate the application efficacy of re-operation and interventional embolization in treat-ment of patients with post-operative recurrence of liver cancer. Methods 62 cases of post-operative recurrence of liver cancer were randomly divided into the operation group and the embolization group,they were treated with re-operation and interventional embolization respectively.The WBC,AFP and long-term survival before and after surgery before and after treatment of two groups were observed. Results The WBC had no significant changes before and after surgery in operation group,the WBC significantly declined after surgery in embolization group,compared with the operation group, the difference was statistically significant (P<0.05).After treatment,the AFP level of both groups significantly declined (P<0.05),but the decline was more significant in the operation group,compared with the embolization group,the differ-ence was statistically significant (P<0.05).The survival rates of one-year,two-years and three-years in the operation group were significantly higher than those of the embolization group (P<0.05). Conclusion Again re-operation in the treatment of post-operative recurrence of liver cancer can improve the level of AFP,improve the long-term survival,for patients with poor body condition,interventional embolization has important advantages.%目的：探讨再次手术与介入栓塞在肝癌术后复发患者中的应用效果。方法将62例肝癌术后复发患者随机均分为手术组和栓塞组，分别给予再次手术切除与介入栓塞治疗，观察两组患者治疗前后WBC、AFP的变化及远期生存情况。结果手术组患者治疗前后WBC无明显变化，栓塞组患者治疗后WBC水平明显下降，且与手术组比较差异有统计学意义(P<0.05)；两组患者治疗后AFP水平均明显下降(P<0.05)，手术组下降更为明显，与栓塞组比较差异有统计学意义(P<0.05)；手术组患者1、2、3年的生存率均明显高于栓塞组(P<0.05)。结论再次手术切除治疗肝癌术后复发可改善患者的AFP水平，提高远期生存率，对于机体情况较差的患者，介入栓塞有重要优势。