腮腺原发性恶性淋巴瘤五例并文献复习

摘要

目的 探讨原发性腮腺恶性淋巴瘤的临床特点.方法 收集首都医科大学附属北京朝阳医院2002年1月至2010年10月5例腮腺恶性淋巴瘤患者病历资料并进行回顾性分析并结合文献进行讨论.结果 本研究5例患者均长期生活在偏远农村,主要表现为腮腺区肿块生长迅速,偶有疼痛；实验室检查淋巴细胞均增高；均经病理组织学确诊为B细胞来源非霍奇金淋巴瘤,其中黏膜相关结外边缘区B细胞淋巴瘤2例、滤泡性淋巴瘤Ⅱ级1例、弥散性大B细胞淋巴瘤1例,B小淋巴细胞淋巴瘤1例.结论 腮腺恶性淋巴瘤临床特征为非特异性,确诊较为困难,手术切除合并病理组织学检查是诊治的主要手段.%Objective To document the cliniclpathologic features of primary malignant lymphoma of the parotid gland based on analysis of our cases.Methods Five cases of malignant parotid gland lymphoma admitted in the Department of central sugery in Beijing Chaoyang hospital of capital medical university between January 2002 and May 2010 were reviewed.Results Five patients were long-term living in remote rural areas,mainly for parotid masses rapid growth,occasional pain; the laboratory examination results found lymphocytes were increased,the pathological diagnosis were B-cell non-Hodgkin's lymphoma.The pathology features of the five cases included 2 cases of mueosaassociated lymphoid tissue lymphoma,1 case of Follicular lymphoma,1 case of diffuse large B cell lymphoma,1 case of Small lymphocytic lymphoma.Conclusions Primary malignant lymphoma of the parotid gland has no clinical specificity,thus its diagnosis is very difficult and a misdiagnosis is easily made.The major diagnostic tool is the combination with postoperative pathology.