LEEP手术联合生长因子治疗慢性宫颈炎720例疗效观察

摘要

目的:探讨慢性宫颈炎患者LEEP手术治疗后联合生长因子使用对创面恢复的疗效.方法:对720例宫颈糜烂患者采用LEEP手术治疗,术后分为实验组和对照组,每组各360例.实验组手术创面使用外用重组人碱性成纤维细胞生长因子和甲硝唑粉末,对照组只使用甲硝唑粉末,观察记录术后情况.结果:实验组治愈率为99.70%、对照组治愈率为88.89%;术后实验组流液(9.0±2.5)d,对照组流液(15.0±2.2)d,实验组术后出血23例,占6.38%,对照组术后出血61例,占16.94%;以上各项指标实验组与对照组比较,差异均有统计学意义(P<0.05).结论:LEEP术后配合生长因子的使用能有效提高治愈率、缩短术后流液时间并减少术后创面出血,使用方便,值得临床上推广.%Objective: To discuss the curative effect of growth factors in wound recovery after LEEP surgery in patients with chronic cervicitis. Methods: LEEP surgeries were adopted in 720 cases of patients with cervical erosion. All patients were divided into experiment group and control group after surgery, 360 cases in each group. Recombinant human basic fibroblast growth factor and Metronidazole powder were used in surgical wounds in experiment group, and only Metronidazole powder were used in control group, the postoperative conditions were observed and recorded after surgery. Results: The cure rate was 99.7% in experiment group and 88.89% in control group; the time of postoperative liquid flow was (9.0±2.5) d in experiment group and (15.0±2.2) d in control group; 23 cases had postoperative bleeding in experiment group with the ratio of 6.38%, 61 cases had postoperative bleeding in control group with the ratio of 16.94%. Compared with control group, the above experimental indicators were significantly differences in experiment group (P<0.05). Conclusion: LEEP surgery combined with the use of growth factors can effectively improve the cure rate, shorten the time of postoperative liquid flow, reduce the incidence of postoperative wound bleeding and easily use. It is worthy of clinical application.