原发性胆管细胞性肝癌与肝细胞性肝癌的临床观察

摘要

Objective: To explore the clinical feature of primary cholangiocarcinoma and hepatocellular liver cancer.Methods: Retrospectively analyzed the clinical data of primary cholangiocarcinoma and hepatocellular carcinoma, the patients were divided into observstion group (50 cases) and control group (30 cases). Results: The hepatic cirrhosis, AFP masccline rate of observation group were Iower than those of the control group, CA19-9 masccline rate, misdiagnosis rate were hjgher than those of the control group (P＜0.05), primary cholangiocarcinoma were left lobe, not integrated amicula, crinosity, absorbent gland metastasis rate. There were significant differences in two groups (all P＜0.05). The 1 year, 3 years, 5 years survival rate of two groups were no significant difference (all P＞0.05). Conclusion: Primary cholangiocarcinoma is a variant primary liver cancer. Studying the clinicopathologic features is beneficial to improve the differential diagnosis of primary cholangiocarcinoma from hepatocellular curcinoma.%目的:探讨原发性胆管细胞性肝癌与肝细胞性肝癌的临床特点.方法:采用回顾性分析的方法,分析我院收治的原发性胆管细胞性肝癌和肝细胞性肝癌患者的临床资料,将其分为观察组(50例)和对照组(30例).结果:观察组肝硬化、AFP阳性率明显低于对照组,而CA19-9阳性率、误诊率均明显高于对照组(P＜0.05).原发性胆管细胞性肝癌一般位于左叶、无完整包膜、多发,淋巴结转移率较高,两组比较,差异均有统计学意义(均P＜0.05).两组患者1、3、5年生存率比较,差异均无统计学意义(均P＞0.05).结论:胆管细胞性肝癌是原发性肝癌的一种特殊类型.掌握其临床特点,将有助于提高胆管细胞性肝癌与肝细胞性肝癌的鉴别诊断水平.