目的：探讨高频超声在肝硬化及相关疾病诊断中的应用价值。方法选取2013年1月~2015年1月在本院就诊的肝硬化患者144例，对其行常规超声检查，当常规腹部探头显示肝实质回声不均或肝脏浅表组织可疑病变时，加用高频线阵探头进行检查，并对检查出的15个被膜下结节行高频超声造影。结果发现肝被膜下结节92例，腹壁静脉曲张28例，肝细胞肝癌胸壁转移2例，脐疝6例。对其中15个结节行高频超声造影，诊断为肝细胞肝癌（HCC）10个，血管瘤2个，再生结节3个。高频超声诊断被膜下HCC的敏感性为80%，特异性为28.6%，准确性为47.0%。高频超声造影诊断被膜下HCC的敏感性为90%，特异性为71.4%，准确性为76.4%。结论高频超声检查可明显提高肝硬化及相关疾病的诊断正确率。%Objective To explore the application value of high frequency ultrasound in the diagnosis of liver cirrhosis and related diseases. Methods 144 patients with liver cirrhosis who underwent diagnosis and treatment in our hospital from January 2013 to January 2015 were selected to receive regular ultrasound examination. The patients were treated with high frequency linear array probe as supplementary ultrasound examination when liver parenchyma showed uneven echo or pathological changes were suspected on superficial hepatic tissue. In addition, the 15 nodules detected were examined with real-time high-frequency contrast-enhanced ultrasound. Results Hepatic subcapsular nodules were found in 92 cases;abdominal varices were found in 28 cases of hepatocellular carcinoma. There were 2 cases of chest wall metastases, 6 cases of umbilical hernia. Among the 15 nodules that were examined by high frequency ultrasound imaging, 10 were diagnosed as hepatocellular carcinoma (HCC), 2 were diagnosed as hemangioma, and 3 were diagnosed as regeneration nodules. In response to the real-time high-frequency ultrasound, the sensitivity of HCC was 80%, the specificity was 28.6%, and the accuracy was 47.0%. In response to the high-frequency contrast-enhanced ultrasound, the sensitivity of HCC was 90%, the specificity was 71.4%, and the accuracy was 76.4%. Conclusion High-frequency ultrasound could significantly improve the accuracy in the diagnosis of liver cirrhosis and related diseases.
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