肉鸡日粮中25-羟基维生素D3与维生素D3生物学效价比较

摘要

The present study was conducted to compare the relative bioavailability(RBV)of 25-hydroxycholecalcifer-ol(25-OH-D3)to cholecalciferol (VD3)for broilers from 1 to 42 days of age.On the day of hatch,300 female Ross 308 broilers were allotted to 6 treatments with 5 replicates of 10 each.The basal diet contained 0.50% calcium (Ca),0.25%non-phytate phosphorus (NPP),and was not supplemented with VD3.VD3 adding level was 5.0,10.0,20.0 μg/kg and 25-OH-D3 adding level was 2.5,5.0,10.0 μg/kg.The results showed that using body weight gain (BWG)as the criteria,the RBV of 25-OH-D3 to VD3 was 1.78.Using tibia breaking-strength,weight and ash weight as the criteria,the RBV of 25-OH-D3 to VD3 were 2.09,1.82 and 1.73.Using femur weight,length and ash weight as the criteria,the RBV of 25-OH-D3 to VD3 were 1.80,1.65 and 1.81.These data indicated that 25-OH-D3 was approximately 1.81 times as active as vitamin D3 for promoting growth performance and bone mineralization in broiler chickens from 1 to 42 days of age.%为比较肉鸡日粮中25-羟基维生素D3（25-OH-D3）与维生素D3相对生物学效价，选用1日龄罗斯308肉鸡母雏300只，随机分为6个处理组，每处理5个重复，每重复10只。设计6种日粮，在含0.50%Ca、0.25%非植酸磷（NPP），无维生素D3的玉米-豆粕型基础日粮中分别添加3个水平25-OH-D3（2.5、5.0、10.0μg/kg）和3个水平维生素D3（5.0、10.0、20.0μg/kg）。结果显示：（1）以1～42日龄肉鸡体增重评价，25-OH-D3生物学效价是维生素D3的1.78倍；（2）以42日龄肉鸡胫骨强度、重量和灰分重量评价，25-OH-D3生物学效价分别是维生素D3的2.09、1.82和1.73倍；（3）以42日龄肉鸡股骨重量、长度和灰分重量评价，25-OH-D3生物学效价分别是维生素D3的1.80、1.65和1.81倍。综合分析，在1～42日龄肉鸡日粮中，以生长性能和骨骼矿化指标评价，25-OH-D3生物学效价约为维生素D3的1.81倍。