丁二磺酸腺苷蛋氨酸联合复方鳖甲软肝片治疗胆汁性肝硬化疗效观察

摘要

Objective To investigate the clinical effect of succinic acid methionine combined with compound Biejiaruangan tablets in the treatment of biliary cirrhosis.Methods 61 cases of biliary cirrhosis patients in our hospital were selected, they were randomly divided into the control group of 30 cases, the observation group of 31 cases, after 2 weeks of intravenous infusion of succinic acid methionine in the control group, and then 10 weeks of oral succinic acid methionine, the observation group on basis of the control group was given compound Biejiaruangan tablets, and the clinical efifcacy and adverse reactions of the two groups were observed and compared.Results The total effective rate of the observation group (93.55%) was higher than that of the control group (70.00%), the difference was statistically signiifcant (P<0.05); No obvious adverse reactions were found in the two groups.Conclusion Succinic acid methionine combined with compound Biejiaruangan tablets in the treatment of biliary cirrhosis, the curative effect is remarkable, and the safety is higher.%目的：探讨丁二磺酸腺苷蛋氨酸联合复方鳖甲软肝片治疗胆汁性肝硬化的临床疗效。方法抽取我院接收的胆汁性肝硬化患者61例，随机分为对照组30例，观察组31例，对照组静脉滴注2周丁二磺酸腺苷蛋氨酸后，再口服10周丁二磺酸腺苷蛋氨酸治疗，观察组在对照组基础上加服复方鳖甲软肝片，观察比较两组临床疗效及不良反应发生情况。结果观察组总有效率（93.55%）高于对照组（70.00%），差异具有统计学意义（P＜0.05）；两组均未见明显不良反应。结论丁二磺酸腺苷蛋氨酸联合复方鳖甲软肝片应用于胆汁性肝硬化，疗效显著，安全性高。