The discovery of COX-2 provides a novel target developing more effective NSAIDswith fewer side effects On the basis of results from the structure-activity relationships (SAR) ofselective COX-2 inhibitors. we have designed and synthesized some promising compounds.
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机译:Neural activity in the periaqueductal gray and other specific subcortical structures is enhanced when a selective serotonin reuptake inhibitor selectively prevents seizure-induced sudden death in the DBA/1 mouse model of sudden unexpected death in epilepsy