中药复方灌注剂对奶牛乳房炎的防治效果及免疫增强作用

摘要

选取临床型、隐性型和健康型荷斯坦奶牛共80头,用于中药复方灌注剂对奶牛乳房炎的防治及免疫试验,对治疗前后乳中体细胞数(SCC)、乳清中白蛋白(SA)、乳酸脱氢酶(LDH)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、淋巴细胞刺激指数(SI)、嗜中性粒细胞吞噬率和使用前后干奶期乳房炎的发病率进行了研究.结果表明,中药复方灌注剂和抗生素对隐性乳房炎的治愈率分别为94.44％和88.24％,有效率均为100％；对临床型乳房炎的治愈率分别为86.67％和76.92％,有效率为93.33％和84.62％；对干奶期乳房炎的预防效果分别为88.89％和94.12％,而生理盐水对照组发病率高达45.45％.中药复方灌注剂可以极显著降低患病奶牛乳中SCC、SA、LDH、ALT、AST水平(P＜0.01),提高SI和嗜中性粒细胞吞噬率(P＜0.01).试验证实了中药复方灌注剂对奶牛乳房炎有较好的防治效果,能够修复奶牛受损的乳腺上皮细胞,降低受损细胞产生的酶含量和血乳的渗透性,提高患病奶牛机体的免疫机能.%80 dairy cows were selected in order to observe the prevention and cure effect and immunological enhancement of the traditional Chinese medicine complex perfusion fluid to mastitis. The SCC,SA, ALT, AST,LDH,SI,the rate of neutrophil phagocytosis of dairy cows with mastitis during cure were measured,and the incidence of mastitis was observed in the dry period. The results showed that the cure rate of sub-clinical mastitis by traditional Chinese medicine complex perfusion fluid and antibiotics were respectively 94. 44% and 88. 24% ,and the effective rate were 100%. The cure rate of clinical mastitis in dairy cows were respectively 86. 67% and 84. 62%,and the effective rate were 93. 33% and 91. 67%. The preventive effects of mastitis in dry period were 88. 89% and 94. 12%, while the incidence rate in the control group was 42. 86%. The levels of SCC,SA,ALT, AST.LDH were significantly decreased by the traditional Chinese medicine complex perfusion fluid,and the levels of SI and the rate of neutrophil phagocytosis were significantly increased (P<0.01). The experiment showed that the traditional Chinese medicine complex perfusion fluid had a better treat effect on mastitis, which can repair damaged mammary gland epithelial cells and reduce the permeability of the blood-milk and the activity of the enzymes in milk. It can improve the immune function of cows.