奶牛乳糖合成及泌乳相关基因和细胞信号通路的研究进展

摘要

Lactose is a special component of milk and is closely related to milk yield. The factors of influencing lactose synthesis are extensive. The paper reviews the related genes and cell signaling pathways, including glucose transporters, intracel-lular catalytic lactose synthesis enzymes, hormones (insulin, prolactin, growth hormone, leptin, glucocorticoid ), cell factors (IGF-Ⅰ ,IGF-Ⅱ ,EGF) and its main cell signal transduction pathway.%乳糖是乳中的特有成分,与产奶量密切相关.影响牛奶中乳糖合成的因素很多,作者主要综述与其相关基因,包括乳腺葡萄糖转运蛋白、细胞内催化乳糖合成的酶类、与泌乳和乳糖合成相关的激素(胰岛素、催乳素、生长激素、糖皮质激素、瘦素)、细胞因子(IGF-Ⅰ、IGF-Ⅱ、EGF)及其主要的信号传导通路的研究进展.