六种新型5-亚烃基丙二酸亚异丙酯类似物的合成研究

摘要

在邻苯二甲酰亚胺钾催化下,以芳香醛和2,2-亚戊基-1,3-二噁烷4,6-二酮为原料,经Knoevenagel缩合反应,以87.2％～91.4％收率合成了六种新型5-亚烃基丙二酸亚异丙酯类似物,并通过IR、1H NMR、13C NMR对其结构进行了表征.该方法具有反应时间短,收率高,后处理简单,对环境污染较小等优点.%Six kinds of 5-alkenyl-2,2-dimethyl-l,3-dioxane-4,6-dione analogues were synthesized by the Knoevenagel condensation reaction of aromatic aldehydes with 2,2-pentamethylene-l ,3-dioxane-4,6-di-one using phthalimide catalyst- Under above reaction conditions, the product yields achieved up to 87.2% ～ 91.4% . The structure was confirmed by IR, H NMR and C NMR. The present method has the advantages of short time, excellent yields, simple processing and friendly environment.