荧光增白剂ER-I的中试研究

摘要

The fluorescent brightener ER-I was synthesized through Abuzov esterification and Witting condensation with the raw material triethyl phosphite,2-(chloromethyl)benzonitrile and 1,4-phthalaldehyde. The influence factors such as reaction temperature, feeding method and the ratio of raw material were reasearched in detail. Results showed that the optimum reaction condition was as follows;when the ratio of triethyl phosphite : benzyl chloride 1.1 :1.0 was used, temperature of feed was 140 ℃ , the reaction time was 9 h,the total yield 93%. The stabilization of technological condition was confirmed by 6 time tests.%以亚磷酸三乙酯、邻氰基氯苄和对苯二甲醛为原料,经Abuzov酯化反应和Witting反应合成荧光增白剂ER-I,详细研究原料比、反应温度、加料方法对反应的影响.结果表明,最佳的中试工艺为:磷酸酯和氯苄的比为1.1∶1.0,加料温度控制在140℃,反应时间为9h,两步反应总收率93％.6次中试数据验证了该工艺参数稳定可靠.