以肺不张为首发表现肺原发性淋巴瘤1例并文献分析

摘要

目的：研究原发性肺淋巴瘤的临床特点并结合病理、免疫组织化学特征，以期提高对该病的认识及诊断能力。方法分析安医大附属巢湖医院呼吸内科2014年7月23日收治的1例病人，长期误诊近10年，以肺不张为首发表现的淋巴瘤患者的临床和病理资料，并复习相关文献。结果原发性肺淋巴瘤普通病理检查不能鉴别肿瘤的来源，最终经免疫组化确诊为肺淋巴瘤。结论肺原发性淋巴瘤为少见病，临床缺乏特异性，最终确诊须结合肺活检或手术病理及免疫组织化学检查。%Objective To study clinical characteristics and related pathological and immunohistochemical features of primary pulmonary non-Hodgkin’ s lymphoma ( PPNHL) ,and improve its diagnostic accuracy.Methods Investigate one patient with atelectasis who was, misdiagnosed for almost 10 years based on clinical and pathological data of the pulmonary primary lymphoma with atelectasis as the starting profile,and also review relevant literatures.Results General primary pulmonary lymphoma pathologic examination can not i-dentify the source of the tumor,which was finally confirmed by the immunohistochemical diagnosis as pulmonary lymphoma.Conclusion Pulmonary primary lymphoma is rare disease,which clinically lacks specificity.And the final diagnosis should rely on percutaneous or surgical lung biopsy and immunohistochemical examination.