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Increased Orthopaedic Infection Severity in Obesity / Type 2 Diabetes is Associated with Impaired Humoral Immunity and Staphylococcus aureus Adaptation to the Host

机译：肥胖症/ 2型糖尿病中的矫形性感染严重程度增加与体液免疫和金黄色葡萄球菌的适应受损，对宿主有障碍

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作者
Farnsworth, Christopher William.;
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作者单位

University of Rochester.;

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授予单位 University of Rochester.;
学科
学位 Ph.D.
年度 2017
页码 158 p.
总页数 158
原文格式 PDF
正文语种 eng
中图分类 AAI10288485;
关键词
Humoral immunity; Joint replacement; Obesity; Osteomyelitis; S. aureus; Type 2 diabetes;

机译：体液免疫;联合替代;肥胖;骨髓炎;金黄色葡萄球菌;2型糖尿病;

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1. A Humoral Immune Defect Distinguishes the Response to Staphylococcus aureus Infections in Mice with Obesity and Type 2 Diabetes from That in Mice with Type 1 Diabetes [J] . Christopher W. Farnsworth, Cindy T. Shehatou, Robert Maynard, Infection and immunity . 2015,第6期

机译：体液免疫缺陷区分肥胖和2型糖尿病小鼠对金黄色葡萄球菌感染的反应与1型糖尿病小鼠的反应。
2. Exacerbated Staphylococcus aureus Foot Infections in Obese/Diabetic Mice Are Associated with Impaired Germinal Center Reactions, Ig Class Switching, and Humoral Immunity [J] . Farnsworth Christopher W., Schott Eric M., Benvie Abigail, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2018,第2期

机译：肥胖/糖尿病小鼠的黄氏菌病金黄色葡萄球菌脚感染与生发中心反应受损，IG类切换和体液免疫有关
3. Obesity/type 2 diabetes increases inflammation, periosteal reactive bone formation, and osteolysis during Staphylococcus aureus Staphylococcus aureus implant‐associated bone infection [J] . Farnsworth Christopher W., Schott Eric M., Benvie Abigail M., Journal of orthopaedic research . 2018,第6期

机译：肥胖/ 2型糖尿病增加炎症，骨膜反应性骨形成，葡萄球菌金黄色葡萄球菌植入物相关骨感染期间的骨溶解
4. Hydrogel Delivery of Lysostaphin Eliminates Orthopaedic Hardware Infection by Staphylococcus aureus and Supports Fracture Healing [C] . Christopher T. Johnson, James A. Wroe, Rachit Agarwal, Society for Biomaterials annual meeting and exposition . 2018

机译：溶葡萄球菌素的水凝胶递送消除了金黄色葡萄球菌对骨科硬件的感染，并支持骨折愈合
5. Staphylococcus aureus biofilm-mediated infections: Characterization of the host adaptive immune response and its role in chronic infection [D] . Prabhakara, Ranjani. 2010

机译：金黄色葡萄球菌生物膜介导的感染：宿主适应性免疫反应的表征及其在慢性感染中的作用
6. A Humoral Immune Defect Distinguishes the Response to Staphylococcus aureus Infections in Mice with Obesity and Type 2 Diabetes from That in Mice with Type 1 Diabetes [O] . Christopher W. Farnsworth, Cindy T. Shehatou, Robert Maynard, 2015

机译：体液免疫缺陷区分肥胖和2型糖尿病小鼠对金黄色葡萄球菌感染的反应与1型糖尿病小鼠的反应。
7. A Humoral Immune Defect Distinguishes the Response to Staphylococcus aureus Infections in Mice with Obesity and Type 2 Diabetes from That in Mice with Type 1 Diabetes [O] . Christopher W. Farnsworth, Cindy T. Shehatou, Robert Maynard, 2015

机译：体液免疫缺损将肥胖症和2型糖尿病患者的小鼠对小鼠葡萄球菌感染的反应区分了与1型糖尿病的小鼠

Increased Orthopaedic Infection Severity in Obesity / Type 2 Diabetes is Associated with Impaired Humoral Immunity and Staphylococcus aureus Adaptation to the Host

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