Numerical modeling of light distribution for optoacoustic determination of blood effective attenuation coefficient in radial artery

摘要

We modeled three-dimensional light distribution in the radial artery using geometrical parameters of this blood vessel and optical parameters typical for blood in the near-infrared spectral range. The obtained light distributions allowed for calculation of optoacoustic signals detected by transducers on the skin surface. We then compared the calculated signals with optoacoustic signals experimentally measured from tissue phantoms at different effective attenuation coefficients and obtained good correlation. Our data suggest that the light distribution and optoacoustic signal modeling can be used in transducer design and in optoacoustic signal processing for accurate measurement of blood parameters.