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Fluorescent Silica Beads for Detection of Cervical Cancer

机译:荧光硅珠检测宫颈癌

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We present the use of self-assembled fluorescent silica (glass) beads for detection of cervical cancer. The cells from three different individuals (3 normal and 3 tumor) were tested for affinity by using the beads, a few microns glass nanoporous particles which contain florescent dyes sealed inside the pores. We have developed two different methods for detecting the affinity in a Petri-dish. After simple precipitation of the beads onto the cells, the unbounded beads removed by washing. The next method involved using centrifugation for the removal of the unbounded beads. Both methods show unambiguous identification between the normal and tumor cells.
机译:我们目前使用自组装的荧光二氧化硅(玻璃)珠子检测宫颈癌。通过使用珠子,几微米的玻璃纳米多孔颗粒,其中包含密封在孔中的荧光染料,测试了来自三个不同个体(3个正常肿瘤和3个肿瘤)的细胞的亲和力。我们已经开发了两种不同的方法来检测培养皿中的亲和力。在将珠子简单沉淀到细胞上后,通过洗涤除去未结合的珠子。下一种方法涉及使用离心去除未结合的珠子。两种方法均显示出正常细胞与肿瘤细胞之间的明确识别。

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