APPLICATION OF BIOENCAPSULATED PROTEINASES AND PEPTIDES FOR WOUND HEALING

摘要

These data in an animal model demonstrate that thrombin or synthetic peptides bioencapsulated in PVCL-CaAlg polymer dressings or PLGA microparticles may be of therapeutic use for clinical situations. These data demonstrate the role of these agents in the inflammatory and proliferative phases of tissue repair in vivo. These data show that these agents may accelerate a number of wound healing processes in vivo. It is anticipated that the development of new formulations based on the proposed bioencapsulated peptides will contribute to a new generation of effective dressings with drug controlled release for wound therapy.