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Microbial transformations of artemisinin by Cunninghamella echinulata and Aspergillus niger

机译:棘孢青霉菌和黑曲霉对青蒿素的微生物转化

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摘要

Microbial transformations of artemisinin 1 by Cunninghamella echinulata (AS 3.3400) and Aspergillus niger (AS 3.795) were carried out. Two products, 10β-hydroxyartemisinin 2 and 3α-hydroxydeoxyartemisinin 3, were obtained. Their structures were identified on the basis of chemical and spectroscopic data. 10β-Hydroxyartemisinin is a new compound.
机译:进行了Cunninghamella echinulata(AS 3.3400)和黑曲霉(AS 3.795)对青蒿素1的微生物转化。获得了两种产物10β-羟基青蒿素2和3α-羟基脱氧青蒿素3。根据化学和光谱数据鉴定了它们的结构。 10β-羟基青蒿素是一种新化合物。

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