Asymmetric transfer hydrogenation over rhodium catalysts in the presence of chiral diamine

摘要

The reactions of hydrogen transfer from 2-propanol on acetophenone and keto acid esters (methyl pyruvate, methyl benzoyl formate) in the presence of the system {[Rh(COD)Cl]_2-(R,R)-2-base}, where ((R,R)-2 is N~1,N~2-bis (thiophen-2-yl-methyl)cyclohexane-1,2-diamine), was studied. Hydrogen transfer proceeds both on metal complexes of rhodium(I) with diamine (R,R)-2 and on chiral modified RhNPs.