The Rhodium(I)-Catalyzed Alkylation of Aryl Sulfonamides with Alkenes through a Bidentate Chelating System and Related Mechanistic Studies

摘要

Sulfonamides are important molecules that are found in a variety of biologically active structural motifs. Many of these molecules show extensive chemical and biological activities and are found in drugs such as celecoxib and gliclazide. Given the fact that many sulfonamide compounds are highly biologically active, the synthesis of sultams from sulfonamide derivatives has been extensively studied by various research groups.