Effects of different levels of vegetable meal inclusion inreplacement for fish meal in practical diets for sea bass (D. labrax) on GUT histology and nutrigenomic activity

摘要

The inclusion of plant-protein sources in aquafeed has increased due to the limited amount and increasing cost of fish-meal available for production of animal feeds (Burr et ah, 2012). One of the greatest challenges for the aquafeed industry isto reduce fishmeal levels in feed further and increase the amount of plant protein and ingredient diversity in diets of carnivorous fishes. Fish meal free diets have been successfully used but problems related to some anti-nutritional factors lave not allowed so far a total substitution offish meal. In addition, higher inclusion level of vegetable meals, cause reduces weight gain and feed efficiency as well as morphological changes of the digestal intestinal epithelium (Buttle etal, 2004). Although several studies have reported change in growth performance and gut morphology in fish in response to vegetable meals inclusion, few have investigated gene expression and underlying mechanism (Murray et al, 2011). In this work we would like to study the mechanism that affect the utilization of pant products in aquafeed, focusing on the modulation in intestinal nutrient absorption capacity, their assimilation processes during the feeding time and the nutrigenomic effect of Ike vegetable sources.