Effectiveness Test Antimicrobial Infusion Gotu Kola Leaf Extract (Centella Asiatical) On The Growth Staphylococcus Aureus

摘要

Infection is a disease that causes tissue damage. One cause of skin infections is bacteria Staphylococcus aureus. Utilization of natural materials as traditional medicine in Indonesia is now increasing. Centella Asiatica is one of the nutritious plants for medicine, contains active antibacterial components such as saponin or asiatikosida, alkaloid, flavonoids, and tannins. Saponins or asiaticocides are lipophilic which can form complex compounds with cell membranes through hydrogen bonds, then destroy the permeability of bacterial cell walls. This research is to test the effectivity of antimicrobial substances contained in the extract of Leaf kola leaf infusion as a traditional medicine to the growth of Staphylococcus aureus, with the descriptive survey design method to find out the effectiveness of Inca leaf infusion extract zone (Centella Asiatica L) to bacteria Staphylococcus aureus. Result: The concentration formed inhibition zone of bacterial growth Staphylococcus aureus is 25% concentration average 7.25 mm, 50% average 11.3 mm, 75% average 12,75 mm, and 100% average 17,6 mm. Conclusion: Leaf kola infusion extract (Centella Asiatica L) on the growth of Staphylococcus aureus forming inhibit zone at concentrations 25%, 50%, 75%, and 100%.