Clinical Implications of Multiplexed Cytokine Analysis in Canine Diseases

摘要

The importance and complexity of cytokine effects cannot be overstated. Cytokines are known to play important roles in a wide range of pathologic conditions spanning all organ systems in every species studied. As our knowledge of the physiology of individual cytokines expands and our ability to measure multiple cytokines in smaller biological samples increases, we gain insight into the significance and function of each cytokine and the importance of cytokine networks. In this review, we highlight the benefits of multiplex cytokine analysis, summarize clinical and experimental reports that have used this technology in dogs, and discuss the strengths and limitations of data analysis and interpretation in these studies.