Correlation of Blood Lipid Profile, Blood Lipid Ratio and Cystatin C in Patients with Hyperthyroidism

摘要

To investigate the correlation among serum lipids and their ratios and cystatin C (CysC) in patients with hyperthyroidism. authors respectively chose fifty patients of hyperthyroidism, subclinical hyperthyroidism and the control group. TC, TG and LDL-C in the hyperthyroidism and subclinical hyperthyroidism groups were significantly lower than those in the control group (P<0.01); TC/HDL-C, TG/HDL-C, LDL-C/HDL-C, LCI, and non-HDL-C in the hyperthyroidism group were significantly higher than those in the subclinical hyperthyroidism and control groups; TC/HDL-C and TG/HDL-C in the subclinical hyperthyroidism group were significantly higher those in the control group while LDL-C/HDL-C, LCI, and non-HDL-C were significantly lower than the control group. LCI decrease being the most significant followed by LDL-C/HDL-C. The thyroid hormones mostly correlated with TC, followed by non-HDL-C, LDL-C and LCI. The level of CysC in the hyperthyroidism and subclinical hyperthyroidism groups was significantly higher and there was also significant difference regarding this level between both groups (P<0.05). The author came to the conclusion that the changes of serum lipid ratios in patients with hyperthyroidism and subclinical hyperthyroidism were more obvious than single indicator; and their CysC level was also significantly higher than that of control group. Dynamic monitoring of blood lipid ratios and CysC level could be an optimized combination item for the transformation from subclinical hyperthyroidism to hyperthyroidism and prediction of hyperthyroidism complicated with CHD.