Antibacterial Activities and Interactions Study of Ternary Lanthanide Schiff Base and Nitrogen-heterocyclic Complexes Bind to DNA

摘要

In this work, a series of ternary rare earth complexes were synthesized with salicylidene glycine schiff base (Sal-GlyK) as anion ligand and 2, 2'-bipyridine (bipy), 1, 10-phenanthroline (phen) as neutral ligand. The antibacterial activities and interactions between calf thymus DNA (ct-DNA) in Tris-HCl (pH=7.1) and the complexes were investigated by UV-Vis spectrophotometry, fluorescence quench experiment and viscosity measurement. The antibacterial activities of the complexes are all better than the ligands, and the complexes with the bigger planarity ligands are better than the small one.