Space systems design for research on the interaction of osteoblast-like cells and biomaterials (hydroxyapatite particles and titanium) in microgravity environment

摘要

Microgravity and ionizing radiations are some of the special condition that characterize the space environment. These conditions cause major changes in human bodies, or in biomedical samples; in particular, the bone tissue in microgravity conditions, lack of mechanical loading which is one of the main stimulus to bone remodelling needed, loose elasticity and toughness. In 2014 a cooperation between GAUSS srl. (Group of Astrodynamic for the Use of Space System, Rome, Italy), the University of Brasilia (UnB, Brasilia, Brazil) and the State University of Sao Paulo (UNESP, Botucatu, Sao Paulo, Brazil) has been started to study in orbit the effects of the exposure of osteoblast-like cells, responsible to forming-up a new bone, to gold standard biomaterials (hydroxyapatite particles and titanium).