Synthesis of PVP Coated Superparamagnetic Iron Oxide Nanoparticles with a High Saturation Magnetization

摘要

Superparamagnetic iron oxide nanoparticles (SPION) were synthesized by one pot coprecipitation method at room temperature in the presence polyvinylpyrrolidone (PVP). X-ray powder diffraction (XRD), transmission electron microscopy (TEM), and vibrating sample magnetometer (VSM) were used to analysis of PVP-SPION. The physiochemical properties of PVP-SPION are compared to Peptized-SPION. The XRD patterns confirmed that the structure of as-synthesized sample is magnetite with cubic structure system. In TEM results, the image of PVP-SPION displayed that the size of particles was 15.6 nm with narrower size distribution and also the PVP played important role to minimize the agglomeration of SPION. Finally, the high saturation magnetization value of PVP-SPION (53.0 emu/g) indicate the as-synthesized sample has a great potential as a contrast agent for MRI.