Titania nanotube arrays load with Ibuprofen by solvothermal and its release behavior

摘要

In this study, the vertically aligned titania nanotube arrays (TNTs) was fabricated on the surface of titanium substrate in fluoride-containing electrolytes via self-ordering electrochemical anodization. The prepared TNTs loaded with ibuprofen (IBU) by solvothermal to achieve a local drug delivery system and its release properties were investigated. The samples were characterized by field emission scanning electronic microscope(FE-SEM), X-ray diffraction(XRD), Fourier transform infrared(FT-IR). The results indicated that the IBU drug molecules were successfully loaded on the surface of TNTs and the drug release shows a sustained release process. It suggested that TNTs as drug carrier had the properties of sustained release which have a good application prospect in biomedical field.