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Material Flow Modelling for Environmental Exposure Assessment - A Critical Review of Four Approaches Using the Comparative Implementation of an Idealized Example

机译:环境暴露评估的材料流量建模 - 使用理想化示例的比较实施对四种方法的关键综述

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Newly developed materials such as engineered nanomaterials are produced in increasing amounts and applied in a growing number of products. Once released to the environment, they can pose a hazard to ecosystems and human health. To assess potential risks, the exposure of the material to humans and the environment has to be determined. For many materials such as engineered nanomaterials, a quantitative measurement of environmental concentrations is not feasible. Material flow models can be used to determine these concentrations indirectly by predicting material flows in the environment. Several modelling approaches can be applied to represent existing knowledge about the flows of materials into and between environmental media or compartments and to consider the uncertainty and variability of the input parameters. In this study we evaluate four existing approaches with regard to their capabilities for indirect exposure assessment, focusing on their ability to treat uncertainty. We first explain how we preselected the four most promising modelling approaches: material flow analysis, system dynamics, material flow networks, and probabilistic material flow analysis. We then define a set of evaluation criteria based on the requirements of environmental exposure assessment and develop a simplified example system that is designed to test these criteria. Based on the comparative modelling and implementation of the example system, we discuss the capabilities and limitations of the approaches and indicate what is missing for a reliable environmental exposure prediction using material flow modelling.
机译:新开发的材料如工程化的纳米材料是在越来越多的量中产生并且在越来越多的产品中应用。一旦释放到环境,他们就可以对生态系统和人类健康构成危害。为了评估潜在的风险,必须确定材料对人类的暴露和环境。对于诸如工程纳米材料的许多材料,环境浓度的定量测量是不可行的。材料流模型可用于间接通过预测环境中的材料流间接确定这些浓度。若干建模方法可以应用于对环境媒体或隔间之间的材料流和在环境介质或隔间之间的现有知识以及考虑输入参数的不确定性和可变性。在这项研究中,我们评估了四种关于其间接暴露评估的能力的现有方法,重点关注他们治疗不确定性的能力。我们首先解释我们如何预检第四种最有前途的建模方法:材料流量分析,系统动力学,材料流量网络和概率材料流动分析。然后,我们根据环境曝光评估的要求定义一组评估标准,并开发一个旨在测试这些标准的简化示例系统。基于示例系统的比较建模和实施,我们讨论了方法的能力和限制,并指出了使用材料流模型的可靠环境曝光预测缺少的内容。

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