UV Protective Effect of Anthocyanin Extract from Lonicera Caerulea var. Edulis

摘要

In the present study, we investigated the protective effect of anthocyanin extract from Lonicera caerulea var. edulis (LCA) on UVC-induced lipid and protein peroxidation using lecithin and Bull Serum Albumin (BSA) in vitro model. We also investigated the protective effect of anthocyanin on UVC induced cell injury in Spleen lymphocytes of mouse via MTT and comet assays. Peroxidation of lecithin and BSA generated by exposure to UVC radiation was significantly decreased by addition with various concentrations of LCA. Moreover, LCA exhibited an inhibitory effect on DNA damage induced by UVC radiation when compared with the control group, the DNA damage decrease at the LCA concentration of 50-200μg/ml, in comet assay. These results indicate that LCA has certain protective effect to ultraviolet radiation damage.