Cyclic Carbonate End Functional Block Copolymers of Poly (ε-caprolactone) and Poly(methyl methacrylate) or Polystyrene by Combined Ring-Opening Polymerization and Atom Transfer Radical Polymerization Methods

摘要

Block copolymers have received a great deal of research activity in contemporary macromolecular science because of their remarkable ability to spontaneously assemble into nanoscale polymeric architecture and find potential use in numerous nanotechnologies. Polyester-polyacrylate copolymers are known as support for controlled drug delivery. Living and living/controlled polymerization methods or combination of them not only produces well-defined but the variety of block copolymers otherwise such block copolymers are not possible. In this paper, we herein report the synthesis of cyclic carbonate end functional PCL-b-PMMA and PCL-b-PS by using bromopolyesters, initially synthesized by ring-opening polymerization (ROP) of poly(ε-caprolactone) (PCL), as macroinitiators for the atom transfer radical polymerization (ATRP) of methyl methacrylate (MMA) and styrene.