Seeking a New Anti-Skin-Aging Material: Piceatannol and Its Derivatives from Passion Fruit (Passiflora edulis) Seed

摘要

Passion fruit, the fruit of Passiflora edulis, is grown in tropical regions, such as South America and South Asia. The presence of a large amount of polyphenols have been discovered in the seed of passion fruit with piceatannol (3,4,3',5'-tetrahydroxy-trans-stilbene) being the major constituent. Derivatives of piceatannol were also detected. We have focused on the effect of passion fruit on skin health using cultured human melanoma and fibroblast cells, to investigate the inhibition of melanogenesis and promotion of collagen synthesis. Positive effects were obtained. Piceatannol and its derivatives were found to be responsible for the effects observed for passion fruit seed extracts.