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Exposure of arsenic and male reproductive impairment—epidemiological and experimental study

机译:砷和男性生殖损伤流行病学和实验研究的暴露

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Since the early 1980s community are suffering from chronic arsenic toxicity due to exposure through arsenic contaminated groundwater used as drinking water in eight districts of West Bengal and forty four districts of Bangladesh. The water concentration of underground arsenic contamination ranging from below 50 μg/L to above 500 μg/L in different parts of West Bengal, i.e., Murshidabad, Nadia, 24-Parganas (North & South) and Malda was observed (Das & Roy Chowdhur, 2006). Major clinical manifestations of As exposure are hyper pigmentation, keratosis, weakness, anemia, burning sensation of eyes, swelling of legs, liver fibrosis and chronic lung disease. The effect of As in relation to male reproductive function is not well established (WHO, 1981; Pershagen, 1983). Therefore, both epidemiological and experimental study were undertaken to ascertain the effect of As on male reproductive function, if any.
机译:自20世纪80年代初期以来,群体患有慢性砷毒性因砷污染地下水暴露而被用作丹孟加拉邦的八个地区的八十四个地区的饮用水。观察到地下砷污染的水浓度范围为50微克/升至于西孟加拉邦,即Murshidabad,Nadia,24杆(北&南北)和马尔达(Das&Roy Chowdhur) ,2006)。作为曝光的主要临床表现为高色素沉着,角化症,弱点,贫血,眼睛灼热感,腿部肿胀,肝纤维化和慢性肺病。与男性生殖功能相关的影响不是很好的(世卫组织,1981年; Pershagen,1983)。因此,进行了流行病学和实验研究,以确定与男性生殖功能的影响,如果有的话。

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