Angiomatoicl fibrous histiocytoma: fact and myth

摘要

Angiomatoid fibrous histiocytoma is a diagnosis of considerable confusion for several reasons. First, two different entities hide behind this diagnosis, one a variant of dermatofibromas with prominent hemorrhage, also known as aneurysmal fibrous histiocytoma, the other a low grade malignancy of uncertain differentiation, previously classified among malignant fibrous histiocytoma (MFH) as its angiomatoid variant. Secondly, the concept of MFH itself is problematic and nowadays opinion leaders in soft tissue pathology regard MFH more a reaction pattern than a specific disease. Thirdly, this seems also to be true for atypical fibroxanthoma, the dermal analoge of MFH, which is an important differential diagnosis in this instance. Based on a case of angiomatoid (previously malignant) fibrous histiocytoma I will try to bring some order into this perplexing field of soft tissue pathology.