Synthesis, characterization, crystal structure and DNA-binding studies of transition metal hydrazone complexes

摘要

Three new complexes containing salicylaldazine (HL) ligand were synthesised by reacting suitable precursor complex [MCl_2(PPh_3)_2] with the ligand (where M = Cu(II) or Ni(II) or Co(II)). The new complexes were characterised by various spectral studies such as IR, UV-Vis,1H NMR,EPR,fluorescence and elemental analyses. The binding modes of the complexes with HS-DNA have been studied by UV-Vis absorption titration. Binding of the complexes with bovine serum albumin (BSA) protein has been investigated using UV-visible, fluorescence and synchronous fluorescence spectroscopic methods. Redox behaviour of the complexes has been investigated by cyclic voltammetry.