HINDERED TRANSPORT OF POLYELECTROLYTES IN SINGLE CYLINDRICAL NANOPORES PREPARED BY FOCUSED ION BEAM MILLING IN POLYMETHYLMETHACRYLATE MEMBRANES(Abstract)

摘要

Transport in nanopores is dependent on the nature of the electrical communication between the pores and the surrounding environment. Three-dimensional integrated microfluidic devices can be fabricated by using nanocapillary array membranes (NCAM) as electrically switchable gates between two vertically separated microfluidic channels. The gate isolates the fluidic environments between the microchannels and, when a voltage is applied, selectively allows ions and analytes to move between the channels. To obtain a better understanding of this selectivity, a single pore is substituted and the transport of polyelectrolyte-containing fluids is monitored by conductivity and laser-induced fluorescence (LIF) measurements. The data obtained is compared with the results of molecular dynamic simulations to gain insight into the critical properties that govern transport at nanometer-scale dimensions.