Perianal fistula is a chronic inflammatory, ulcerative disease of the perianal tissues that is seen almost exclusively in the German Shepherd dog. The exact etiology of this disease has not been determined as evidenced by the failure of studies that have been performed to investigate a possible immunological, bacterial, endocrine, or anatomic basis for the disease. Consequently, although many different treatment methods have been proposed for this problem, none of those reported are routinely successful in controlling the disease.
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