Oxidized Cellulose Nanofiber for Hemostatic Materials

摘要

In this study, oxidized cellulose nanofiber was prepared from squeeze dried Nata de Coco sheet by the oxidation system of HNO_3/H_3PO_4-NaN02 at 30 °C for 24 hours. The ratio between HNO_3 and H_3PO_4 was 1:3 v/v and the concentration of NaNO_2 was 1.4% w/v. The carboxyl content and %yield of oxidized cellulose nanofiber from Nata de Coco (Nata-OC) was 28.6% and 68.4%, respectively. Then the Nata-OC was treated by several types of bases. Sodium hydroxide (NaOH) or triethanolamine (TEA) treated Nata-OC showed superior in gelation property to the original Nata-OC. The powder of base-treated Nata-OC gave stable Nata-OC aqueous dispersion, which might be applicable for spray-typed materials. The test papers obtained from 10% of base-treated Nata-OC dispersion showed good blood agglutinating property as same as dry sheet of pure Nata-OC. Moreover, the dispersion of base-treated Nata-OC could be coated on the surface of gauze without any additive.