Some Chromatographic Peculiarities of Polymer-Mineral Packing Materials with Octadecyl- and Butyl-Functional Groups

摘要

Some peculiarities of behavior of columns packed by polymer-mineral packing materials in reversed-phase high-performance liquid chromatography (RP-HPLC) regime have been considered as compared with columns containing conventional C_(18)-phase by example of Waters Symmetry C_(18) column. Poly-octadecyl methacrylate-butyl acrylate (poly-ODMA-BA) and polyoctadecyl methacrylate-bu-tylacrylate-maleic anhydride (poly-ODMA-BA-MA) have been used as polymer phases. And micro-spherical silica gels (MS) having following characteristics: specific surface area (S_(sp.)) 80-100 m~2/g; total pore sorption volume (V_Σ) 0.56-1.00 cm~3/g; average pore diameter (d_(av.)) 30 nm have been applied as initial materials of inorganic origin. It has been shown by means of NMR method that above mentioned functional groups are actually fixed on the surface of silica carrier.