Immunogenicity study of a flexible dose PCV type 1-type 2 chimera killed virus vaccine

摘要

Porcine circovirus-associated disease (PCVAD), caused by porcine circo-virus type 2 (PCV2), has become the most economically important emerging disease worldwide, affecting pigs primarily between 5 to 18 weeks of age with clinical signs of progressiveweight loss, dyspnea, tachypnea, jaundice, anemia and mortality up to 30%.' SUVAXYN~R PCV2 (Porcine Circo-virus Vaccine Type 1-Type 2 Chimera, Killed Virus, USDA Product Code 19K5.R1) was licensed by Fort Dodge Animal Health on 24 April 2006, with a label claim of: "For the vaccination of healthy pigs as an aid in the prevention of PCV2 viremia and as an aid in the control of lymphoid depletion caused by PCV2. For herds that use a single dose program, vaccinate pigs intramuscularly at 3 weeks of age orolder with a single 2 mL dose", "For herds that use two (1 mL) dose program, vaccinate pigs intramuscularly at 3 weeks of age or older followed by a second dose 3 weeks later."