FORMATION OF POLYMER VESICLES FROM MICRODROPLETS OF POLYION COMPLEX AND EXAMINATION OF THEIR PHYSICOCHEMICAL PROPERTIES IN MICROFLUIDIC CHAMBER

摘要

This paper presents a direct observation of a non-trivial formation process of individual giant polymer vesicles, i.e., direct formation of vesicles from microdroplets of polyion complex (PIC) and the optimum condition for the formation of the PIC vesicles, providing a basis for an efficient mass-production. In addition, encapsulation of guest polymers and their retention within the PIC vesicle are demonstrated as well as modification of property of the PIC membrane by crosslinking of the con-stituent polymers. All experiments were achieved in a microfluidic chamber which can control solution conditions with keeping targeted objects under the view field of the optical microscope.