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HOMOMORPHISMS OF PROBABILISTIC GENE REGULATORY NETWORKS

机译:概率基因监管网络的同性态

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In this paper we study finite dynamical systems with n functions acting on the same set X, and probabilities assigned to these functions, that it is called Probabilistic Regulatory Gene Networks (PRN) in [3]. This concept is the same or a natural generalization of the concept Probabilistic Boolean Networks (PBN), introduced by I. Shmulevich, E. Dougherty, and W. Zhang in [5], Particularly the model PBN has been using to describe genetic networks and has therapeutic applications, see [6]. In PRN the most important question is to describe the steady states of the systems, so in this paper we pay attention to the idea of transforming a network to another without lost all the properties, in particular the probability distribution. Following this objective we develop the concepts of homomorphism and ε-homomorphism of probabilistic regulatory networks, since these concepts bring the properties from one networks to another. Projections are special homomorphisms, and they always induce invariant subnetworks that contain cycles and steady states.
机译:在本文中,我们研究了具有在相同组X上作用的N个功能的有限动态系统,以及分配给这些功能的概率,即[3]中称为概率调节基因网络(PRN)。这一概念是I. Shmulevich,E. Dougherty和W. Zhang在[5]中介绍的概念概率布尔网络(PBN)的相同或自然概括,特别是Zhang,特别是PBN一直在使用来描述遗传网络和有治疗应用,见[6]。在PRN中,最重要的问题是描述系统的稳定状态,所以在本文中,我们注意了将网络转换为另一个,没有丢失所有属性,特别是概率分布。在此目的之后,我们培养了概率监管网络的同态和ε-同性恋的概念,因为这些概念将属性从一个网络带到另一个网络。预测是特殊的同性恋,它们总是诱导包含循环和稳定状态的不变子网。

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