COMPARATIVE PROTEOGENOMIC ANALYSIS OF COLISTIN-DEPENDENCE IN ACINETOBACTER BAUMANNII

摘要

The multi-drug resistant bacteria A. baumannii belong to the group of human opportunistic pathogens responsible for most common life threatening nosocomial infections. The resistance of A. baumannii to the last-resort antibiotic colistin is increasing and, recently, a high rate of colistin dependence has been demonstrated [1, 2]. However, the mechanisms of antibiotic resistance and dependence are not yet fully understood.