Crohn's disease (CD) of the small intestine (regional granulomatosis enteritis) is one of the internal organ diseases that is difficult to diagnose. The absence of clear symptoms, the presence of extraintestinal manifestations and the difficult visual observation of most of the small intestine lead to diagnostic difficulties in CD. This disease was described about 75 years ago by BB Crohn, L Ginsberg and GD Oppenheimer, but to date its unusual clinical picture is still being investigated.This chapter gives a retrospective analysis of small intestinal CD diagnosis, as well as an analysis of clinical, X-ray, and endoscopic signs of this disease. The aim of this retrospective analysis is to improve early diagnosis of the disease.
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