Pathological observation of the atheromatous abdominal aorta of rabbits treated by HIFU

摘要

OBJECTIVE: To study the pathological changes of the atheromatous abdominal aorta of rabbits after high-intensity focused ultrasound (HIFU) treatment. METHODS: After being subdivided into two groups, the research group and the control group, experimental rabbits were exposed to HIFU (0.8 MHz/10000 W cm-2). HE staining and special elastic fibers staining were used to study the changes of morphology and ultrastructure of vascula endothelial cells and smooth muscle cells at the very day, the fifth day and the tenth day respectively after being exposed to HIFU. TRESULTST: After HIFU treatment, the vascula endothelial cells of abdominal aorta were damaged, or even eliminated. And derangement, breakage and solution took place to elastic fibers. TCONCLUSIONT: In both groups, coagulation necrosis in rabbit abdominal aorta occurred to some degree. And there was no statistical difference between the research group and the control group. So did that in the individual subgroups.