Transition Metal Nanoparticles on Nano-Level-Controlled Carbon Supports:Efficient Preparative Method of Optically Pure Binaphthyl Derivatives

摘要

Enantiomerically pure 1,1'-bi-2-naphthyls such as 1,1'-bi-2-naphthol (BINOL),2,2'-diainino-1,1'-binaphthyl (DABN) and their derivatives (1) are known to be highly useful chiral auxiliaries in the field of asymmetric synthesis.1 The introduction of appropriate substituents at the 3,3'- and/or 6,6'-positions of the original binaphthyl framework (1') is the common method for tuning up their performances.In comparison with such classical modification,recent researches have shown that the chiral catalysts derived from 5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthyls (Hg-binaphthyls:2) sometimes exhibited higher asymmetric induction than the parent 1,1'-bi-2-naphthyls in many asymmetric reactions.