首页> 外文会议>Asia-Pacific Bioinformatics Conference >A NOVEL CLUSTERING METHOD FOR ANALYSIS OF BIOLOGICAL NETWORKS USING MAXIMAL COMPONENTS OF GRAPHS
【24h】

A NOVEL CLUSTERING METHOD FOR ANALYSIS OF BIOLOGICAL NETWORKS USING MAXIMAL COMPONENTS OF GRAPHS

机译:一种使用图形最大组件分析生物网络的一种新型聚类方法

获取原文

摘要

This paper proposes a novel clustering method for analyzing biological networks. In this method, each biological network is treated as an undirected graph and edges are weighted based on similarities of nodes. Then, maximal components, which are denned based on edge connectivity, are computed and the nodes are partitioned into clusters by selecting disjoint maximal components. The proposed method was applied to clustering of protein sequences and was compared with conventional clustering methods. The obtained clusters were evaluated using P-values for GO (GeneOntology) terms. The average P-values for the proposed method were better than those for other methods.
机译:本文提出了一种用于分析生物网络的新型聚类方法。在该方法中,每个生物网络被视为一个未向图形的图形,并且基于节点的相似性加权边缘。然后,计算基于边缘连接的最大组件,并通过选择不相交的最大分量来划分为聚类的节点。将该方法应用于蛋白质序列的聚类,并与常规聚类方法进行比较。使用P值(Geneontology)术语来评估所得簇。所提出的方法的平均p值优于其他方法。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号