Dr. Kalhan has given us a very detailed presentation of the methyl cycle, in which he showed us the first human pregnancy data on transmethylation and trans-sulfuration rates in American women. The key finding there was an increase in transmethylation and a decrease in transsulfuration rates as pregnancy progressed; we have measured these rates in India as well [1]. Unlike American women, the Indian women did not show an increase in transmethylation rates in the third trimester, while transsulfuration rates on the other hand actually increased.
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